Eurofins Biomnis code

PARV

Synonyms

• B19 - IgG/IgM serology
• Erythema infectiosum
• Erythrovirus B19 - IgG/IgM serology
• Fifth disease - IgG/IgM serology

Specialty

Infectious

Clinical significance

Human parvovirus infects erythropoietic stem cells and causes erythema infectiosum (also called fifth disease), an epidemic disease, mainly affecting children, which is characterized by fever and rash. In certain individuals (usually those with some abnormality affecting either their hemoglobin or their red blood cell membrane), infection with human parvovirus can lead to acute hemolysis. Infected adults often experience inflammation of multiple joints which can last a matter of weeks. Neurological complications are rare. Primary infection of women during the first five months of pregnancy can cause hydrops fetalis with ascites and severe, sometimes fatal anemia. Parvovirus B19 cannot be cultured and diagnosis of infection with this organism depends on the detection of viral DNA by PCR assay in the blood or, if it is a pregnant woman that is concerned, in amniotic fluid. IgG antibodies are long-lived

Preanalytics

• 1 x 1 mL :
• serum
•   Reftrigerated

• A tube specifically for this analysis : No

Methodology

Chemiluminescence

Turnaround time

2 days