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Pre-eclampsia - risk estimation - serum

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Eurofins Biomnis code

PECLA

Synonyms

  • Pre-eclampsia
  • Pre-eclampsia risk calculation
  • PIGF

Clinic significance

PlGF (Placental Growth Factor) is, together with PAPP-A, a biochemical marker for pre-eclampsia. Assays are performed during the first trimester of pregnancy. It is possible to calculate an risk of early-onset (before 34 weeks of gestation) or late-onset pre-eclampsia. This calculation of risk includes data about the patient (BMI, smoker/non-smoker, geographic origin, etc.) the history (number of viable pregnancies, history of pre-eclampsia, hypertension) and pregnancy underway (dating: date of the ultrasound and craniocaudal length) in addition to blood pressure and Doppler of uterine arteries.

Prenalytics

  • 3 mL
  • Serum (1 specific tube for pre-eclampsia screening)
  • Refrigerated

Further information

  • Sample must be collected between 11.0 and 13.6 weeks of amenorrhoea
  • Arterial blood pressure should be taken on both arms at the same time; if not, a single arm will suffice.
    The period between the ultrasound scan, the taking of blood pressure and sample collection
    must not exceed 10 days.
  • Risk assessment is possible for monofoetal pregnancies only
  • Enclose the specific clinical information form (R4-INTGB: Pre-eclampsia)
  • Non hemolysed, non-icteric, non lipemic sample. Sample must be centrifuged as quickly as possible and international samples must be frozen within 4 hours of sampling.
    Please conserve an additional sample in your serolibrary until you have received the result.

Specific equipment available

[To be translated]


Methodology

Fluoro-Immunoassay (time resolved)

Turnaround time

1 week


Pathologist(s) in charge
Biomnis Lyon
Specialty
Down Syndrome screening and foetal biochemistry
Contact(s)
Dr Corinne SAULT
Dr Alain LIQUIER
Phone(s)
+334 72 80 73 75
+334 72 80 23 61