Eurofins Biomnis code

PF4

Synonyms

• Anti-heparin antibodies
• Anti-platelet factor 4 antibodies
• Heparin - PF4 - anti-antibodies
• Heparin-induced thrombopaenia - screening
• HIT
• HIT - screening
• PF4 - heparin - anti-antibodies
• Screening for heparin-induced thrombopaenia
• VITT

Specialty

Haematology

Clinical significance

A diagnosis of heparin-induced thrombocytopenia is indicated if platelet numbers fall either gradually or suddenly (to less than 100 x 109/L) at any point after the fifth day of treatment (either curative or preventive) with unfractionated or low molecular weight heparin. The likelihood of thrombocytopenia is very low beyond day 21 of treatment. Such thrombocytopenia is usually due to sensitization to heparin complexed with Platelet Factor 4.

Preanalytics

• 1 mL :
• Citrated Plasma
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : No

Further information

Attach completed information form (ref: R19)
Please supply the clinical pathology probability score if available (i.e. 4T score)
Indiquer spécifiquement si il s'agit d'une recherche dans un contexte de suspicion de VITT post-vaccination COVID 19
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.

Documents to download

• Specific clinical information form (R19-INTGB)

Methodology

Immunology assay automated in chemiluminescence

Turnaround time

2 days