Eurofins Biomnis code

PREK

Synonyms

• Fletcher factor

Specialty

Haematology

Clinical significance

Prekallikrein is a zymogen which, when acted upon by Factor XII or XIIa, forms the serine protease, plasma kallikrein which cleaves high molecular weight kininogen to form bradykinin. Prekallikrein is involved in the initial, "contact phase" of the intrinsic process of blood coagulation.This "contact phase" does not seem to be crucial in physiological terms because deficiencies in either Factor XII, high molecular weight kininogen or prekallikrein are not associated with any kind of bleeding disorder.

Preanalytics

• 1 mL :
• Citrated Plasma
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : Yes

Further information

1 individual aliquot for this analysis.
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.

Methodology

Chronometric method

Turnaround time

1 month