[-2]pro-PSA - Phi score calculation - serum

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Eurofins Biomnis code

PRPSA

Synonyms
  • Health Index
  • new index for prostate cancer
  • New prostatic cancer marker
  • Phi
  • Phi index
  • proPSA
  • Prostate Health Index
  • PSA2
  • P2PSA
Specialty

Biochemistry


Clinical significance

The PHI, Prostate Health Index is an index based on the measurement of a new serum marker for prostate cancer, [-2] proPSA. [-2] proPSA is an isoform of PSA, almost exclusively expressed by prostate cancer cells (unlike total PSA). Its combination with total PSA and free PSA in the calculation of pH allows the specificity of detection of prostate cancer to be improved significantly, and consequently significantly reduces indications for biopsies.

Preanalytics
  • A tube specifically for this analysis : No
Further information

Samples should be centrifuged and frozen within 3 hours of collection
In order to calculate the PHI (Prostate Health Index), [-2] proPSA, free PSA and total PSA are measured using the same technology; therefore it is not possible to use a referred result for free PSA and total PSA


Methodology

CMIA

Turnaround time

6 days


Testing Laboratory

Biomnis Ivry