Eurofins Biomnis code

PTHRP

Synonyms

• Endocrinology
• Parathormone-related protein
• PTH-like
• PTH-related peptide
• PTHrP

Specialty

Biochemistry

Clinical significance

A peptide secreted by epidermoid cysts involving the ear, nose and throat region and the lung, by tumors of the ovary and breast, and by certain forms of leukemic cells. The active site of this peptide is structurally related to that of parathyroid hormone and it has similar effects in bone and kidney tissue, inducing hypercalcemia, hypophosphoremia and increased nephrogenic cyclic AMP.

Preanalytics

• 1 mL :
• EDTA plasma + Aprotinine - non haemolysed
•   FROZEN
• 1 hour

• A tube specifically for this analysis : No

Further information

Sample on special tube (EDTA + Aprotinin) supplied on request.
Freeze the sample within 1 hour after sampling
Centrifuge rapidly at refrigerated temperature

Specific equipment available

• T2 : EDTA + aprotinine tube

Methodology

Radioimmunoassay

Turnaround time

2 weeks