Eurofins Biomnis code

RICCT

Synonyms

• Anti-Rickettsia conorii, typhi antibodies - IgG
• Mediterranean Boutonneuse fever - serology
• R. mooseri
• Rickettsia prowazekii
• Rickettsie
• rocky mountain fever
• [To be translated]

Specialty

Infectious

Clinical significance

The etiologic agent of boutonneuse fever. Its reservoir is mammals (mainly dogs, cattle, rabbits and rodents) and transmission to humans occurs via the bite of infected ticks. The disease is characterized by acute fever, an ulcerating primary lesion (the "tache noire"), lymphadenopathy and generalized erythema. There may also be conjunctivitis. Nervous and cardiac complications are rare. Diagnosis usually depends on serological analysis with evidence of either seroconversion or high levels of specific IgM antibodies. For R. typhi we perform the search for IgM and IgG. However, for R. conorii we only carry out the search for IgG (the IgM of the tested kit being not very specific).

Preanalytics

• 1 mL :
• serum (do not use 10 mL tube)
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

IgG and IgM screening for R. typhi, titration if positive. IgG screening for R. conorii, titration if positive

Methodology

Immunofluorescence

Turnaround time

3 days