Testosterone - man
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TH
Synonyms
- Bound testosterone
- Endocrinology
- Total testosterone
Specialty
Biochemistry
Clinical significance
The major androgenic hormone. In males, 95 % of it is produced by interstitial (Leydig) cells and 5 % in the adrenal gland. In females, it is synthesized in the ovaries and the adrenal gland. Testosterone secretion is regulated by LH in males (negative feedback). It controls differentiation, the development of secondary male characteristics and, by acting together with FSH on Sertoli cells, spermatogenesis.In males, testosterone levels depend on testicular endocrine activity and decrease after 70 years of age. Levels are also decreased if testicular Leydig cell function is impaired (associated with elevated levels of LH) and in gonadal insufficiency. Testosterone levels are high in subjects taking testosterone and in hyperthyroidism.
Methodology
chimiluminescence (CMIA)
Turnaround time
1 day
Biomnis Ivry