Pre-eclampsia sFlt-1 et PlGF - Predictive test - sFlt-1/PlGF ratio - serum

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Eurofins Biomnis code

TPREE

Synonyms
  • Pre-eclampsia
  • Preeclampsia
  • sFIt-1
Specialty

Down Syndrome screening and foetal biochemistry


Clinical significance

The predictive test is for patients between 20 and 37 weeks of gestation, at risk of pre-eclampsia with at least one warning sign. A low sFlt-1/PlGF ratio (< 38) enables predicting the absence of pre-eclampsia (and complications) at 1 week (NPV 99.3%).

Preanalytics
  • 2 mL ((volume impératif)) :
  • Serum (1 specific tube for pre-eclampsia screening)
  •   Refrigerated
  • A tube specifically for this analysis : No
Further information

Sampling from Week 20 of pregnancy
The sample must be centrifuged as quickly as possible, within 4 hours by the latest.
For the French Overseas Territories and other international consignments: FROZEN < 4H IMPERATIVE
Please ensure to confirm the sample and conception date (date of the first trimester ultrasound and crown rump length (CRL)).
1 individual aliquot for this analysis.

Specific equipment available
  • [To be translated]

Methodology

Electrochemiluminescence

Turnaround time

2 days


Testing Laboratory