HER2 - Human Epidermal growth factor Receptor 2 - c-erbB-2 protein - serum Referred Test

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Eurofins Biomnis code

ERBB2

Synonyms
  • c-erbB-2
  • HER2 ECD - extracellular domain
Specialty

Biochemistry


Clinical significance

HER2 ECD is the cleaved circulating extracellular part of the HER2 growth factor receptor which can be over-expressed in some breast tumours. Over-expression of this receptor detected by means of immuno-chemistry involves treatment with trastuzumab (Herceptin), a monoclonal antibody targeting HER2. The serum HER2 concentration is useful for monitoring patients treated with trastuzumab.

Preanalytics
  • A tube specifically for this analysis : No
Further information

Sample to be frozen within 1 hour. Home sampling is not advisable.
Use the specific request form B9-INTGB: Oncology-Solid tumors


Methodology

Enzyme-immunoassay

Turnaround time

2 weeks


Testing Laboratory

Refered Test


Caption

Referred TestThe pre-analytical conditions and prices are defined on the basis of the requirements of the performing laboratory.