NGS "LUNG1" panel: AKT1, ALK, BRAF, DDR2, EGFR, HER2, FGFR1, FGFR2, FGFR3, KIT, KRAS, MAP2K1, MET, NRAS, PDGFRA, PIK3CA, PTEN, STK11, TP53

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Eurofins Biomnis code

POUM2

Synonyms
  • companion test
  • NGS
  • oncology
  • solid tumor
  • targeted therapy
Specialty

Genetics

Clinical significance

The NGS "LUNG2" panel approach expands the range of tested mutations in the genes implicated in resistance mechanisms for targeted therapies, emerging markers for targeted therapies or immunotherapy response, or potential targets for clinical research. This approach should be complemented by targeted FISH tests.

Preanalytics
  • A tube specifically for this analysis : No
Further information

Use the specific request form B9-INTGB: Oncology-Solid tumors
The use of the S25UK transport bag is Mandatory.
Attach the anatomopathological report

Specific equipment available
  • S25 : Envelope Genetics and Molecular Oncology
Documents to download
Methodology

Targeted sequencing of cancer genes (NGS) : -Library : AmpliSeq Library PLUS for Illumina Custom Panel V1 - Amplicon-based targeted library preparation method -NGS Platform : MiSeq Illumina - Flowcell : microV2 (2x150pb) - Paired-end reads -Analysis software : Miseq control Software version 2.6.2.1 /SeqOne Platform v1.2 - CE Pipeline version : SomaVar v1.4 CE -Limit of detection : 5% -Minimum depth accepted : 500x -Human genome version : Hg19

Turnaround time

10 business days

Testing Laboratory

Biomnis Lyon

Contact(s)
Customer Care